104549-94-2Relevant academic research and scientific papers
Sila-Pharmaca, 36. - Sila-Procyclidine: A New Synthesis as well as Investigations of the Peripheral and Central Anticholinergic Activity
Tacke, Reinhold,Pikies, Jerzy,Linoh, Haryanto,Rohr-Aehle, Regine,Goenne, Sigrid
, p. 51 - 58 (2007/10/02)
Starting with Cl3SiCH2Cl, sila-procyclidine (1b) as well as its derivatives 2b (sila-trihexyphenidyl), 3b, and 4b (sila-cycrimine) were prepared by a new six-step synthesis with a total yields of 16 (1b), 19 (2b), 8 (3b) and 7percent (4b), respectively. -
