104550-20-1Relevant academic research and scientific papers
Investigation on the Kinetics of the Formation of E- and Z-Enols in the Thermolysis of 2-Diazo-1,3-dimesityl-1,3-propanedione in Nucleophiles
Meier, Herbert,Wengenroth, Horst,Lauer, Wolfgang,Vogt, Walter
, p. 1643 - 1646 (2007/10/02)
Thermolysis of the diazo compound 1 in ethanol and piperidine or morpholine leads to enols 3a-c, respectively, of β-ketocarboxylic acid derivatives.Z- and E-configurations are in an equilibrium.The determination of the rate constants demonstrates that primarily the Z-forms are generated preferentially; however, in the equilibrium state the E-isomers finally dominate in the media used for thermolysis.On the contrary, the Z-isomers containing an intramolecular hydrogen bridge predominate in aprotic, apolar or moderately polar solvents.
β-Ketocarboxylic Esters with trans-Enolization
Meier, Herbert,Lauer, Wolfgang,Krause, Volker
, p. 3382 - 3393 (2007/10/02)
Open-chained β-ketocarboxylic esters 10/11, existing predominantly in the E-configuration 2 of the enol form, can be generated by the introduction of mesityl groups.The energy gain by the intramolecular hydrogen bridge in the Z-configurations 1 is compens
