1045720-18-0Relevant academic research and scientific papers
First asymmetric synthesis of piperidine alkaloid (-)-morusimic acid D
Yu, De-Sheng,Xu, Wei-An,Liu, Liang-Xian,Huang, Pei-Qiang
, p. 1189 - 1192 (2008)
The first asymmetric synthesis of (-)-morusimic acid D, a 2,3-trans-2,6-cis-2-methyl-6-substituted piperidin-3-ol containing alkaloid is reported. The key steps are the reductive alkylation of N,O-diprotected 3-hydroxyglutarimide, a stepwise reductive alkylation, and an asymmetric aldol-type reaction using a modified Evans chiral auxiliary. Georg Thieme Verlag Stuttgart.
