10458-14-7Relevant articles and documents
Oxidation of alcohols to aldehydes and ketones using TBHP as an oxidant over LaMO3 (M = Cr, Mn, Co, Ni, Fe) perovskites
Singh, Savita J.,Jayaram, Radha V.
, p. 299 - 308 (2012)
Oxidation of a wide variety of structurally and electronically diverse primary and secondary alcohols to aldehydes and ketones was carried out using a novel catalytic system of LaCrO3 and tert-butyl hydroperoxide (TBHP) under solvent-free conditions. The methodology afforded the desired carbonyl compounds in good to excellent yields, and the catalyst can be reused several times with no significant loss in activity. Copyright Taylor & Francis Group, LLC.
Oxidation of alcohols with catalytic amounts of IBX
Schulze, Agnes,Giannis, Athanassios
, p. 257 - 260 (2006)
Herein we present a catalytic IBX-based method for the oxidation of alcohols. Using this system a variety of benzylic alcohols were transformed to aldehydes in good yields whereas secondary alcohols were easily converted to ketones. Primary aliphatic alcohols were oxidised to the corresponding carboxylic acids. 2-lodobenzoic acid can also be used instead of IBX. Georg Thieme Verlag Stuttgart.
Chromium trioxide on H-Y zeolite: Rapid oxidation of alcohols to carbonyl compounds in solventless system using microwaves
Mirza-Aghayan, Maryam,Heravi, Majid M.
, p. 785 - 789 (1999)
In an environmentally benign solventless system, alcohols are rapidly oxidized to carbonyl compounds using HY-zeolite supported chromium trioxide as an oxidant under microwave irradiation.
Intramolecular hydrogen transfer reaction: Menthon from isopulegol
Schaub, Thomas,Ruedenauer, Stefan,Weis, Martine
, p. 2575 - 2577 (2014)
The flavor menthon (isomeric mixture of (-)-menthon and (+)-isomenthon) was obtained in good yields and selectivities by a solventless ruthenium catalyzed isomerization of the homoallylic alcohol (-)-isopulegol. In contrast to most previous assumptions on such isomerization reactions, this reaction follows an intermolecular pathway, with menthol and pulegon being the central intermediates in this transformation.
Oxidation of secondary alcohols using molecular oxygen and benzaldehyde in the absence of metal catalysts
Choudary, Boyapati M.,Sudha, Yepuri
, p. 1651 - 1655 (1996)
A simple and convenient method for the oxidation of secondary alcohols using molecular oxygen, benzaldehyde in 1,2-dichloroethane in the absence of metal catalysts is described for the first time.
Oxidation of Benzylic and Secondary Alcohols to Carbonyl Compounds by NaBrO3-NH4Cl Reagent in Aqueous Acetonitrile
Shaabani, Ahmad,Ameri, Majid
, p. 100 - 101 (1998)
NaBrO3 combined with NH4Cl is found to be an efficient reagent for the conversion, in aqueous acetonitrile and under mild conditions, of benzylic and secondary alcohols into aldehydes and ketones, respectively.
Cu/SiO2: An improved catalyst for the chemoselective hydrogenation of α,β-unsaturated ketones
Ravasio, Nicoletta,Antenori, Marisa,Gargano, Michele,Mastrorilli, Piero
, p. 3529 - 3532 (1996)
Cu/SiO2 can be conveniently used for the quantitative hydrogenation of conjugated enones to saturated ketones, also when another olefinic bond is present in the molecule, under very mild conditions. Molecular H2 or 2-propanol can be used as hydrogen source.
Preparation and Use of Tetra-n-butylammonium Per-ruthenate (TBAP reagent) and Tetra-n-propylammonium Per-ruthenate (TPAP reagent) as New Catalytic Oxidants for Alcohols
Griffith, William P.,Ley, Steven V.,Whitcombe, Gwynne P.,White, Andrew D.
, p. 1625 - 1627 (1987)
Tetra-n-butylammonium per-ruthenate (Bun4N)(RuO4) and tetra-n-propylammonium per-ruthenate (Prn4N)(RuO4), with N-methylmorpholine N-oxide, function as mild catalitic oxidants for the high yield conversion of alcohols to aldehydes and ketones and are competitive with more conventional reagents.
Engineering the "missing Link" in Biosynthetic (-)-Menthol Production: Bacterial Isopulegone Isomerase
Currin, Andrew,Dunstan, Mark S.,Johannissen, Linus O.,Hollywood, Katherine A.,Vinaixa, Maria,Jervis, Adrian J.,Swainston, Neil,Rattray, Nicholas J. W.,Gardiner, John M.,Kell, Douglas B.,Takano, Eriko,Toogood, Helen S.,Scrutton, Nigel S.
, p. 2012 - 2020 (2018)
The realization of a synthetic biology approach to microbial (1R,2S,5R)-(-)-menthol (1) production relies on the identification of a gene encoding an isopulegone isomerase (IPGI), the only enzyme in the Mentha piperita biosynthetic pathway as yet unidentified. We demonstrate that Δ5-3-ketosteroid isomerase (KSI) from Pseudomonas putida can act as an IPGI, producing (R)-(+)-pulegone ((R)-2) from (+)-cis-isopulegone (3). Using a robotics-driven semirational design strategy, we identified a key KSI variant encoding four active site mutations, which confer a 4.3-fold increase in activity over the wild-type enzyme. This was assisted by the generation of crystal structures of four KSI variants, combined with molecular modeling of 3 binding to identify key active site residue targets. The KSI variant was demonstrated to function efficiently within cascade biocatalytic reactions with downstream Mentha enzymes pulegone reductase and (-)-menthone:(-)-menthol reductase to generate 1 from 3. This study introduces the use of a recombinant IPGI, engineered to function efficiently within a biosynthetic pathway for the production of 1 in microorganisms.
OXYDATION D'ALCOOLS PAR L'ANHYDRIDE CHROMIQUE DANS LES CONDITIONS DU TRANSFERT DE PHASE SOLIDE-LIQUIDE.
Gelbard, Georges,Brunelet, Thierry,Jouitteau, Catherine
, p. 4653 - 4654 (1980)
Catalytic amounts quaternary ammonium salts afforded efficient oxidation of alcohols by chromium trioxide at room temperature in organic solvents.
