104581-18-2Relevant academic research and scientific papers
Iodine-Promoted Semmler–Wolff Reactions: Step-Economic Access to meta-Substituted Primary Anilines via Aromatization
Wang, Shi-Ke,You, Xia,Zhao, Da-Yuan,Mou, Neng-Jie,Luo, Qun-Li
, p. 11757 - 11760 (2017/09/07)
An atom- and step-economic access to an array of unprotected meta-substituted primary anilines was disclosed using the Semmler–Wolff reaction, promoted by molecular iodine. Therein, noble metal catalysts and inert atmosphere are unnecessary while the forcing reaction conditions and the lengthy synthesis can be avoided. The synthetic utility of this approach is evident in the de novo syntheses of three bioactive molecules with good total yields.
ELIMINATION OF THE NITRILE GROUP FROM o-AMINONITRILES-IV; A NEW AND EFFICIENT SYNTHESIS OF 3,5-DIARYLAMINOBENZENES FROM ARYLIDENEMALONODINITRILES AND 1-ARYLETHYLIDENEMALONODINITRILES
Sepiol, Janusz,Milart, Piotr
, p. 5261 - 5266 (2007/10/02)
A synthesis of a variety of 5'-amino-m-terphenyls (6) and 3,5-diarylaminobenzenes through an efficient elimination of cyano groups from 5'-amino-4',6'-dicyano-m-terphenyls (4) using sodium hydroxide in ethanol at 220 deg, is described.The starting o-amino
