1046045-66-2Relevant academic research and scientific papers
Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins
Kamisuki, Shinji,Shirakawa, Takashi,Kugimiya, Akira,Abu-Elheiga, Lutfi,Park Choo, Hea-Young,Yamada, Kohei,Shimogawa, Hiroki,Wakil, Salih J.,Uesugi, Motonari
supporting information; experimental part, p. 4923 - 4927 (2011/09/19)
Fatostatin, a recently discovered small molecule that inhibits activation of sterol regulatory element-binding protein (SREBP), blocks biosynthesis and accumulation of fat in obese mice. We synthesized and evaluated a series of fatostatin derivatives. Our
