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1046135-95-8

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1046135-95-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1046135-95-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,6,1,3 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1046135-95:
(9*1)+(8*0)+(7*4)+(6*6)+(5*1)+(4*3)+(3*5)+(2*9)+(1*5)=128
128 % 10 = 8
So 1046135-95-8 is a valid CAS Registry Number.

1046135-95-8Upstream product

1046135-95-8Downstream Products

1046135-95-8Relevant articles and documents

Citral derived amides as potent bacterial NorA efflux pump inhibitors

Thota, Niranjan,Koul, Surrinder,Reddy, Mallepally V.,Sangwan, Payare L.,Khan, Inshad A.,Kumar, Ashwani,Raja, Alsaba F.,Andotra, Samar S.,Qazi, Ghulam N.

, p. 6535 - 6543 (2008)

Monoterpene citral and citronellal have been used as starting material for the preparation of 5,9-dimethyl-deca-2,4,8-trienoic acid amides and 9-formyl-5-methyl-deca-2,4,8-trienoic acid amides. The amides on bioevaluation as efflux pump inhibitors (EPIs) against Staphylococcus aureus 1199 and NorA overexpressing S. aureus 1199B bacteria resulted in the identification of several of these as potent EPIs. Many of these amides have been shown to possess potency higher or equivalent to known EPIs such as reserpine, verapamil, carsonic acid, and piperine. In this communication, we report a convenient synthesis of alkenyl amides, their bioevaluation and identification as efflux pump inhibitors against S. aureus.

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