1046146-11-5

Basic information

• Product Name: (3-bromo-phenyl)-(3,5-dimethoxy-phenyl)-methanol
• Synonyms: (3-bromo-phenyl)-(3,5-dimethoxy-phenyl)-methanol
• CAS NO: 1046146-11-5
• Molecular Weight: 323.186
• Mol File: 1046146-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-bromo-phenyl)-(3,5-dimethoxy-phenyl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3-bromo-phenyl)-(3,5-dimethoxy-phenyl)-methanol(1046146-11-5)
• EPA Substance Registry System: (3-bromo-phenyl)-(3,5-dimethoxy-phenyl)-methanol(1046146-11-5)

Safety Data

• Hazardous Substances Data: 1046146-11-5(Hazardous Substances Data)

Upstream product

• 111762-31-3 3-bromophenyl magnesium bromide 

Downstream Products

• 951892-07-2 (3-bromo-phenyl)-(3,5-dimethoxy-phenyl)-methanone 

Relevant articles and documents

Exploring the substituent effects on a novel series of C1′-dimethyl-aryl Δ8-tetrahydrocannabinol analogs

The synthesis and characterization of novel C1′-phenyl-substituted Δ8-THC analogs were previously reported by our laboratory. Within this small series of compounds, the C1′-dimethyl phenyl group was found to impart 13.5-fold selectivity for the CB2 receptor with a Ki 0.91 nM. The current study expands on the previous report by evaluating the effects of aromatic ring substitution on CB1 and CB2 receptor subtype binding and selectivity. The ring substituents synthesized in this study include aliphatic, halogen, nitrile, and acetamido functional groups. In addition, the isosteric replacement of the phenyl group by thiophene was evaluated. The anti-glioma activities of selected compounds were evaluated in vitro and compared to the lead compound 2.