1046148-81-5Relevant academic research and scientific papers
Synthesis and transformations of ethyl 3-(benzoylamino)-1H-indole-2- carboxylates
Cucek, Karmen,Vercek, Bojan
, p. 1741 - 1746 (2008)
A number of ethyl 3-(benzoylamino)-lH-indole-2-car-boxylates were prepared by heating ethyl 2-(benzoylamino)-3-(phenylhydrazono)propanoates with polyphosphoric acid. The reaction of ethyl 3-(benzoylamino)-5-chloro-lH-indole- 2-carboxylate with hydrazine hydrate resulted in the formation of the debenzoylated hydrazide. Hydrolysis of the same ester with aqueous sodium hydroxide afforded 3-(benzoylamino)-5-chloro-lH-indole-2-carbox-ylic acid, which on heating underwent a decarboxylation reaction to givei N-(5-chloro-lH-indol- 3-yl)benzamide.
