10463-02-2

Basic information

• Product Name: ethyl 2-(2,4,5-trichlorophenoxy)propionate
• Synonyms: ethyl 2-(2,4,5-trichlorophenoxy)propionate;2-(2,4,5-Trichlorophenoxy)propanoic acid ethyl ester
• CAS NO: 10463-02-2
• Molecular Formula: C11H11Cl3O3
• Molecular Weight: 297.56224
• EINECS: 233-947-5
• Mol File: 10463-02-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 351.9°Cat760mmHg
• Flash Point: 137.2°C
• Appearance: /
• Density: 1.357g/cm³
• Vapor Pressure: 3.99E-05mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: ethyl 2-(2,4,5-trichlorophenoxy)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2,4,5-trichlorophenoxy)propionate(10463-02-2)
• EPA Substance Registry System: ethyl 2-(2,4,5-trichlorophenoxy)propionate(10463-02-2)

Safety Data

• Hazardous Substances Data: 10463-02-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H11Cl3O3/c1-3-16-11(15)6(2)17-10-5-8(13)7(12)4-9(10)14/h4-6H,3H2,1-2H3

Upstream product

• 84028-89-7 ethyl (R)-2-trifluoromethylsulfonyloxypropanoate 
• 95-95-4 2,4,5-trichlorophenol 

Relevant articles and documents

Substitution of 2-(Sulfonyloxy)carboxylates with Oxygene and Sulfur Nucleophiles without Racemization

The ethyl 2-(sulfonyloxy)propionates (S)-1a-c react with phenolates formed from 2 and with carboxylates 8 to give the respective 2-(aryloxy)- (R)-3 and 2-(acyloxy)propionates (R)-9 with inversion of configuration.Due to the high leaving tendency of the triflate group, (S)-1a generally give higher yields of substitution products under milder conditions than the corresponding mesylate (S)-1b and tosylate (S)-1c.In the case of the reaction of malic and succinic acid derivatives only the triflate (S)-10a is converted to the acyloxy compounds (R)-12 with carboxylates 8 atlow temperature (-45 deg C); with the mesylates 10b and the bromide 10d only elimination is observed.Mercaptides and thiophenolates formed from 17 react with (S)-1a-c analogously.With potassium thiocyanate 1a,b react almost exclusively to give the thiocyanate 19; only traces of the corresponding isothiocyanate 20 are obtained.