10463-37-3

Usage

Uses

Used in Scientific Research:
3,5-Dinitro-4-hydroxyphenylacetic acid is used as a reagent or substrate in various chemical reactions for scientific research purposes. Its unique structure and properties make it a valuable compound for exploring new chemical reactions and syntheses.
Used in Chemical Synthesis:
In the field of chemical synthesis, 3,5-dinitro-4-hydroxyphenylacetic acid serves as a key intermediate or building block for the synthesis of more complex organic compounds. Its aromatic ring and functional groups can be further modified or used in the formation of new chemical bonds, contributing to the development of novel molecules with potential applications in various industries.
Used in Analytical Chemistry:
3,5-Dinitro-4-hydroxyphenylacetic acid can be employed as an analytical standard or reference compound in analytical chemistry. Its distinct chemical properties and reactivity can be utilized for the calibration of instruments, validation of analytical methods, or as a benchmark for comparing the performance of different analytical techniques.
Used in Pharmaceutical Development:
Although not explicitly mentioned in the provided materials, 3,5-dinitro-4-hydroxyphenylacetic acid, given its structural features, could potentially be used in the pharmaceutical industry as a precursor or building block for the development of new drugs. Its reactivity and functional groups may allow for the synthesis of bioactive compounds with therapeutic potential.

InChI:InChI=1/C8H6N2O7/c11-7(12)3-4-1-5(9(14)15)8(13)6(2-4)10(16)17/h1-2,13H,3H2,(H,11,12)

Upstream product

• 89723-32-0 4-Acetoxy-phenylessigsaeure-aethylester 
• 55770-69-9 3,5-Dinitro-4-hydroxy-benzylcyanid 
• 156-38-7 4-hydroxyphenylacetate 

Downstream Products

• 1443011-80-0 N-benzyl-2-(4-hydroxy-3,5-dinitrophenyl)acetamide 
• 1443011-77-5 N-benzyl-2-{4-hydroxy-3,5-bis[(thiophen-2-ylmethyl)amino]phenyl}acetamide 
• 1443011-83-3 C₁₅H₁₇N₃O₂ 
• 865798-49-8 (4-methoxy-3,5-dinitro-phenyl)-acetic acid methyl ester 
• 98879-76-6 methyl 2-(3,5-dinitro-4-hydroxyphenyl)acetate 
• 102446-53-7 [3,5-bis-acetylamino-4-(4-methoxy-phenoxy)-phenyl]-acetic acid ethyl ester 
• 861065-72-7 [4-(4-methoxy-phenoxy)-3,5-dinitro-phenyl]-acetic acid ethyl ester 
• 83799-60-4 (4-hydroxy-3,5-dinitro-phenyl)-acetic acid ethyl ester 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of bifunctional thyrointegrin inhibitors: New anti-angiogenesis analogs

Context: Inhibition of pathological angiogenesis. Objective: Obtaining new transactivator, bifunctional, thyroid antagonist, non-toxic anti-angiogenic compounds. Materials and methods: In silico drug design, synthesis in bulk and biological evaluation in chick chorioallantoic membrane (CAM) model. Results: Significant inhibition (range 6573%) at 0.252.0 g/ml doses. Discussion and conclusion: The synthesis of compounds (9), (10), and (11) incorporating long-chain moieties guanidine, urea, methyl amine and, propyl amine substitutions, respectively, into the core molecular framework of tetrac (tetraiodothyroacetic acid) were undertaken. The evaluation of the anti-angiogenic bioactivity of these compounds in the CAM model revealed no loss of activity in comparison with tetrac and XT199, which showed nearly 86% inhibition at dose levels of 1 and 0.5 g/ml, respectively, and validated the concept.