1046338-07-1Relevant academic research and scientific papers
Efficient synthesis of highly substituted indolizinones via iodocyclization and 1,2-shift
Choi, Jihyun,Ge, Hyeong Lee,Kim, Ikyon
experimental part, p. 1243 - 1249 (2009/04/05)
The 5-endo-dig iodocyclization of propargylic alcohols followed by a 1,2-shift provided rapid access to 2-iodoindolizinones, while the 5-endo-trig iodocyclization of allylic alcohols and subsequent dehydroiodination and 1,2-shift led to indolizinones. A number of highly substituted indolizinones were constructed under these mild reaction conditions. Georg Thieme Verlag Stuttgart.
