1046338-97-9

Upstream product

• 1046338-49-1 C₁₈H₁₉INO⁽¹⁺⁾*I^(1-) 
• 1046337-99-8 4,4-dimethyl-1-phenyl-1-(pyridin-2-yl)pent-2-yn-1-ol 

Downstream Products

• 1221509-58-5 C₂₆H₂₃NO 

Relevant academic research and scientific papers

Diversity-oriented construction of highly substituted indolizinones

Rapid generation of a small library of highly functionalized indolizonones was realized by exploiting three palladium-catalyzed cross-coupling reactions of 2-iodoindolizinones which in turn were readily accessed via sequential iodine-mediated cyclization/1,2-shift reactions of propargylic alcohols.

Efficient synthesis of highly substituted indolizinones via iodocyclization and 1,2-shift

The 5-endo-dig iodocyclization of propargylic alcohols followed by a 1,2-shift provided rapid access to 2-iodoindolizinones, while the 5-endo-trig iodocyclization of allylic alcohols and subsequent dehydroiodination and 1,2-shift led to indolizinones. A number of highly substituted indolizinones were constructed under these mild reaction conditions. Georg Thieme Verlag Stuttgart.