1046459-89-5Relevant academic research and scientific papers
A methodology for the synthesis of highly functionalized 2- and 4-aminoquinoline derivatives
Hwang, Bo Hyun,Park, Sung Hee,Choi, Eun Bok,Pak, Chwang Siek,Lee, Hyeon Kyu
, p. 6698 - 6704 (2008)
A methodology for the synthesis of 2- and 4-aminoquinoline derivatives, which takes advantage of selective activation of 2- or 4-substituent of 2-methylsulfanyl-3-acyl-1H-quinolin-4-one 1, has been developed. Since a procedure for formation of 3-aminoquinolinones from the 4-quinolinone 1 was described previously, the new methodology comprises a general methodology for the selective syntheses of three isomeric 2-, 3- and 4-aminoquinoline derivatives starting with the common 4-quinolinone 1.
