1046494-85-2

Basic information

• Product Name: BENZOIC ACID, 2-[(4-FORMYLPHENOXY)METHYL]-, METHYL ESTER
• Synonyms: BENZOIC ACID, 2-[(4-FORMYLPHENOXY)METHYL]-, METHYL ESTER;2-[(4-Formylphenoxy)methyl]benzoic acid methyl ester
• CAS NO: 1046494-85-2
• Molecular Formula: C₁₆H₁₄O₄
• Molecular Weight: 270.27996
• Mol File: 1046494-85-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.208
• CAS DataBase Reference: BENZOIC ACID, 2-[(4-FORMYLPHENOXY)METHYL]-, METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOIC ACID, 2-[(4-FORMYLPHENOXY)METHYL]-, METHYL ESTER(1046494-85-2)
• EPA Substance Registry System: BENZOIC ACID, 2-[(4-FORMYLPHENOXY)METHYL]-, METHYL ESTER(1046494-85-2)

Safety Data

• Hazardous Substances Data: 1046494-85-2(Hazardous Substances Data)

Upstream product

• 2417-73-4 methyl 2-bromomethylbenzoate 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 1296210-21-3 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(10-aminodecylaminomethyl)phenoxymethyl]benzamide 
• 1296210-20-2 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(9-aminononylaminomethyl)phenoxymethyl]benzamide 
• 1296210-19-9 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(8-aminooctylaminomethyl)phenoxymethyl]benzamide 
• 1296210-18-8 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(7-aminoheptylaminomethyl)phenoxymethyl]benzamide 
• 1296210-17-7 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(6-aminohexylaminomethyl)phenoxymethyl]benzamide 
• 1296210-16-6 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(5-aminopentylaminomethyl)phenoxymethyl]benzamide 
• 1296210-15-5 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(4-aminobutylaminomethyl)phenoxymethyl]benzamide 
• 1296210-14-4 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(3-aminopropylaminomethyl)phenoxymethyl]benzamide 
• 1296210-13-3 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(decylaminomethyl)phenoxymethyl]benzamide 
• 1296210-12-2 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(nonylaminomethyl)phenoxymethyl]benzamide 
• 1296210-11-1 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(octylaminomethyl)phenoxymethyl]benzamide 
• 1296210-10-0 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(heptylaminomethyl)phenoxymethyl]benzamide 
• 1296210-09-7 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(hexylaminomethyl)phenoxymethyl]benzamide 
• 1296210-08-6 N-(4-amino-2-methylquinolin-6-yl)-2-[4-(pentylaminomethyl)phenoxymethyl]benzamide 

Relevant articles and documents

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Bivalent ligands constituted by two identical pharmacophores structurally related to the Nociceptin Opioid Receptor (NOPr) antagonist JTC-801 were synthesized and their binding affinities for NOPr were evaluated. The novel ligands are formed by two modifi

Dibenzoxepinone hydroxylamines and hydroxamic acids: Dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity

Hydroxylamine and hydroxamic acid derivatives of a known nonsteroidal antiinflammatory dibenzoxepine series display both cyclooxygenase (CO) and 5- lipoxygenase (5-LO) inhibitory properties. Many of these new dual CO/5-LO inhibitors also exhibit potent topical antiinflammatory activity in the arachidonic acid-induced murine ear edema model. On the basis of their promising profile of in vitro and in vivo activities, hydroxamic acids 24h, 3-(6,11-dihydro-11-oxodibenz[b,e]oxepin-2-yl)-N-hydroxy-N-methylpropanamide (HP 977), and 25, 3-(6,11-dihydrodibenz[b,e]oxepin-2-yl)-N-hydroxy-N- methylpropanamide (P10294), were selected as developmental candidates for the topical treatment of inflammatory skin disorders.