1046790-09-3

Basic information

• Product Name: C₂₆H₃₈N₄O₇
• CAS NO: 1046790-09-3
• Molecular Weight: 518.61
• Mol File: 1046790-09-3.mol

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₈N₄O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₈N₄O₇(1046790-09-3)
• EPA Substance Registry System: C₂₆H₃₈N₄O₇(1046790-09-3)

Safety Data

• Hazardous Substances Data: 1046790-09-3(Hazardous Substances Data)

Upstream product

• 1046790-05-9 C₂₆H₄₀N₄O₈ 

Relevant articles and documents

Synthesis of cyclic peptides via O-N-acyl migration

We describe here a novel and convenient synthesis of head-to-tail cyclic peptide avoiding racemization. Linear depsipeptides including a serine residue as the key element for ester bond formation and acyl transfer were synthesized on 2-chlorotrityl chloride resin. After cleavage from the resin, intramolecular head-to-tail cyclization was performed in solution by C-terminal activation of urethane protected O-acyl serine residue. After removal of the Nα-serine protecting group, the final step consisted in O-N-acyl migration reaction on the 'switch' or 'click' element to restore native cyclic peptides.