1046799-53-4Relevant academic research and scientific papers
Total synthesis of cleomiscosin C via a regioselective cycloaddition reaction of o-quinone
Kuboki, Atsuhito,Maeda, Chie,Arishige, Tetsuya,Kuyama, Kohei,Hamabata, Mami,Ohira, Susumu
, p. 4516 - 4518 (2008/09/21)
We have achieved total synthesis of cleomiscosin C (aquillochin) through regioselective cycloaddition of o-quinone and protected sinapyl alcohol as a key step. During preparation of o-quinone from phenol by IBX oxidation, silyl substituents adjacent to the phenolic hydroxyl group afforded effective inhibition of an undesired oxidative elimination.
