104680-81-1

Basic information

• Product Name: 2-<3'-(2',5'-dioxo-1'-methylpyrrolidinyl)>-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 104680-81-1
• Molecular Weight: 244.293
• Mol File: 104680-81-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-<3'-(2',5'-dioxo-1'-methylpyrrolidinyl)>-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<3'-(2',5'-dioxo-1'-methylpyrrolidinyl)>-1,2,3,4-tetrahydroisoquinoline(104680-81-1)
• EPA Substance Registry System: 2-<3'-(2',5'-dioxo-1'-methylpyrrolidinyl)>-1,2,3,4-tetrahydroisoquinoline(104680-81-1)

Safety Data

• Hazardous Substances Data: 104680-81-1(Hazardous Substances Data)

Upstream product

• 930-88-1 N-methylmaleimide 
• 28752-82-1 2-(allyloxy)benzaldehyde 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 1074-12-0 phenylglyoxal hydrate 
• 29978-83-4 o-propargyloxybenzaldehyde 
• 135-02-4 ortho-anisaldehyde 
• 643-79-8 o-phthalic dicarboxaldehyde 

Relevant articles and documents

X=Y-ZH COMPOUNDS AS POTENTIAL 1,3-DIPOLES. PART 29. THE IMINIUM ION ROUTE TO AZOMETHINE YLIDES. REACTION OF CYCLIC SECONDARY AMINES WITH MONO- AND BI- FUNCTIONAL ALDEHYDES

1,2,3,4-Tetrahydro-isoquinoline and -β-carboline react with a range of mono- and bi- functional aldehydes to give azomethine ylides.The anti-dipole is formed stereospecifically or, in the case of benzaldehyde and 2-methylbenzaldehyde, stereoselectively.The effect of the structure of the aldehyde on the stereochemistry of the derived azomethine ylide is rationalised in terms of steric and electronic effects.Inter- and intra-molecular trapping of the azomethine ylides gives cycloadducts in good yield.