1046812-03-6

Basic information

• Product Name: 2-(4,5-Dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: 2-(4,5-Dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;4,5-Dihydrofuran-3-boronic acid pinacol ester;2-(4,5-dihydro-3-furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1046812-03-6
• Molecular Formula: C₁₀H₁₇BO₃
• Molecular Weight: 196.05118
• Mol File: 1046812-03-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 199.5±50.0 °C(Predicted)
• Appearance: /
• Density: 1.02±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2-(4,5-Dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4,5-Dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1046812-03-6)
• EPA Substance Registry System: 2-(4,5-Dihydrofuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1046812-03-6)

Safety Data

• Hazardous Substances Data: 1046812-03-6(Hazardous Substances Data)

Usage

Uses

4,5-Dihydrofuran-3-boronic Acid Pinacol Ester is a useful reagent in iridium-catalyzed vinicylic C-H borylation.

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 73183-34-3 bis(pinacol)diborane 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 

Relevant articles and documents

Metal-catalyzed reactions of organoboronic acids and esters

Metal-catalyzed B-C and C-C bond-forming reactions of organoboronic acids that have been pursued in the past three decades by our group are summarized in this article. B-C bond-forming reactions for the synthesis of organoboronic acid derivatives include metal-catalyzed addition reactions of pinacolborane or catecholborane (hydroboration), bis(pinacolato)diboron (diboration), and alkylthioboranes (thioboration) to alkenes, alkynes, 1,3-alkadienes, or 1,2-alka-dienes (allenes). Other B-C bond-forming reactions include coupling reactions of pinacolborane or bis(pinacolato)dibor-on for borylation of C-halogen bonds with palladium catalysts and C-H bonds of arenes and alkenes with iridium catalysts. These reactions have provided a convenient new access to aryl-, 1-alkenyl-, allyl-, or benzylboronates. Metal-catalyzed C-C and C-N bond-forming reactions using boronic acid derivatives include synthesis of novel cyclic triolborate salts for palladium- or copper-catalyzed cross-coupling reactions with organic halides or amines, rhodium- or palladium-catalyzed 1,4-addition reactions of arylboronic acids to α,β-unsaturated carbonyl compounds and rhodium-catalyzed addition of aryl- and 1-alkenylboronic acids to aldehydes and imines.