10469-01-9Relevant academic research and scientific papers
Palladium-catalyzed highly regioselective 2-arylation of 2,x-dibromopyridines and its application in the efficient synthesis of a 17β-HSD1 inhibitor
Zhou, Qizhong,Zhang, Bin,Su, Liangjun,Jiang, Tiansheng,Chen, Rener,Du, Tieqi,Ye, Yuyuan,Shen, Jianfen,Dai, Guoliang,Han, Deman,Jiang, Huajiang
, p. 10996 - 11003 (2014/01/06)
2,3- and 2,5-Dibromopyridines reacted with arylboronic acids, catalyzed by Pd(OAc)2/PPh3 in the presence of K2CO 3 in CH3CN/MeOH (2:1) at 50 C for 24 h, to afford 2-arylpyridines in good to high yield
Synthesis of novel 3,5-dichloro-2-arylpyridines by palladium acetate-catalyzed ligand-free suzuki reactions in aqueous media
Hu, Huanan,Ge, Changhua,Zhang, Anjiang,Ding, Lisheng
experimental part, p. 3153 - 3160 (2009/12/09)
A highly efficient palladium acetate-catalyzed ligand-free Suzuki reaction of 2,3,5-trichloropyridine with arylboronic acids in aqueous phase was developed. High yields of 3,5-dichloro-2-arylpyridines, a simple Pd source, absence of ligands, and environme
