10473-42-4

Basic information

• Product Name: 3β-Acetyloxy-5-oxo-5,6-secocholestan-6-oic acid
• Synonyms: 3β-Acetyloxy-5-oxo-5,6-secocholestan-6-oic acid
• CAS NO: 10473-42-4
• Molecular Formula: C₂₉H₄₈O₅
• Molecular Weight: 476.68842
• Mol File: 10473-42-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 573.2°Cat760mmHg
• Flash Point: 176.6°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 1.24E-14mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: 3β-Acetyloxy-5-oxo-5,6-secocholestan-6-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-Acetyloxy-5-oxo-5,6-secocholestan-6-oic acid(10473-42-4)
• EPA Substance Registry System: 3β-Acetyloxy-5-oxo-5,6-secocholestan-6-oic acid(10473-42-4)

Safety Data

• Hazardous Substances Data: 10473-42-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C29H48O5/c1-18(2)8-7-9-19(3)23-10-11-24-22(17-27(32)33)25(13-15-28(23,24)5)29(6)14-12-21(16-26(29)31)34-20(4)30/h18-19,21-25H,7-17H2,1-6H3,(H,32,33)

Upstream product

• 604-35-3 Cholesteryl acetate 
• 6580-09-2 3β-acetoxy-5α-hydroxycholestan-6-one 
• 104596-45-4 3β-acetoxy-cholest-4-en-6-one 
• 84681-02-7 3β-acetoxy-5ξ,6ξ-epidioxy-6ξ-ethoxy-5,6-secocholestane-5ξ-ol 
• 123285-93-8 Acetic acid (3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-5,6-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 14993-76-1 3β-acetoxy-6-oxa-7a-homocholest-4-en-7-one 
• 96478-98-7 Acetic acid (3S,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-5-hydroxy-10,13-dimethyl-6-oxo-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 1256-31-1 3β-acetoxy-5,6-epoxycholestane 

Downstream Products

• 219579-70-1 [(1R,3aS,4R,5S,7aR)-5-((Z)-5-Cyano-1-methylene-pent-4-enyl)-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-yl]-acetic acid 
• 104527-35-7 5,6-seco-5-oxo-3,4-cholesten-6-oic acid 
• 53512-63-3 5,6-seco-5-oxo-cholestan-6-oic acid 
• 14291-09-9 3β-acetoxy-B-norcholest-5-ene 
• 28936-18-7 Acetic acid (3R,3aR,5aS,5bR,8S,12aR,12bS,12cS)-3-((R)-1,5-dimethyl-hexyl)-3a,5b-dimethyl-12-oxo-hexadecahydro-10-oxa-dicyclopenta[a,k]fluoren-8-yl ester 
• 53512-64-4 5,6-Seco-cholestan-5-on-6-saeure-methylester 
• 17007-06-6 B-Nor-cholestadien-(3.5) 
• 67204-86-8 methyl 3β-acetoxy-5-oxo-5,6-seco-cholestan-6-oate 

Relevant articles and documents

3Beta-hydroxy-6-aza-cholestane and related analogues as phosphatidylinositol specific phospholipase C (PI-PLC) inhibitors with antitumor activity.

6-Aza steroid analogues were synthesized as PI-PLC inhibitors. The most active compound, 3beta-hydroxy-6-aza-cholestane (1) showed potent PI-PLC inhibition (IC50 = 1.8 microM), similar to that of the commercially available steroid analogue U73122 (IC50 =

Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase

Silica gel supported pyrolysis of an azido-homo-oxa steroid led to rearrangement, presumably by a mechanism similar to that of solution phase Schmidt fragmentation, to produce a group of novel inhibitors for the oncogenic cell cycle regulator Cdc25A phosp

OXIDATIVE CLEAVAGE OF 1,2-GLYCOLS AND α-HYDROXY KETONES WITH THE JONES REAGENT

The oxidative cleavage of secondary-tertiary 1,2-glycols and α-hydroxy ketones with the Jones reagent proved to be a particularly useful synthetic procedure to form the corresponding ketoacids in excellent yields.