104736-30-3Relevant academic research and scientific papers
Use of Trifluoromethyl Groups for Catalytic Benzylation and Alkylation with Subsequent Hydrodefluorination
Zhu, Jiangtao,Prez, Manuel,Caputo, Christopher B.,Stephan, Douglas W.
supporting information, p. 1417 - 1421 (2016/02/14)
The electrophilic organofluorophosphonium catalyst [(C6F5)3PF][B(C6F5)4] is shown to effect benzylation or alkylation by aryl and alkyl CF3 groups with subsequent hydrodefluorination, thus resulting in a net transformation of CF3 into CH2-aryl fragments. In the case of alkyl CF3 groups, Friedel-Crafts alkylation by the difluorocarbocation proceeded without cation rearrangement, in contrast to the corresponding reactions of alkyl monofluorides.
(1.1.1.1.1)PARACYCLOPHANE AND (1.1.1.1.1.1)PARACYCLOPHANE
Gribble, Gordon W.,Nutaitis, Charles F.
, p. 6023 - 6026 (2007/10/02)
The first syntheses of (1.1.1.1.1)paracyclophane (1) and (1.1.1.1.1.1)paracyclophane (2) are described, featuring a trifluoroacetic acid promoted Friedel-Crafts cycloalkylation as the final step.
