104754-51-0

Basic information

• Product Name: 2-Furancarboxylicacid,tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-(9CI)
• Synonyms: 2-Furancarboxylicacid,tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-(9CI)
• CAS NO: 104754-51-0
• Molecular Formula: C₁₃H₁₃NO₆
• Molecular Weight: 279.24542
• Product Categories: N-CBZ
• Mol File: 104754-51-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Furancarboxylicacid,tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxylicacid,tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-(9CI)(104754-51-0)
• EPA Substance Registry System: 2-Furancarboxylicacid,tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-(9CI)(104754-51-0)

Safety Data

• Hazardous Substances Data: 104754-51-0(Hazardous Substances Data)

Usage

General Description

2-Furancarboxylic acid, tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino]-(9CI) is a chemical compound with a complex molecular structure. It consists of a furan ring with a carboxylic acid group and a tetrahydro-5-oxo-2-[[(phenylmethoxy)carbonyl]amino] side chain. The compound has potential applications in the field of medicinal chemistry and drug development due to its unique structure and functional groups. It may be used as a building block for creating novel pharmaceutical compounds with targeted biological activities. Further research and study are needed to fully understand the potential uses and properties of this chemical.

Upstream product

• 501-53-1 benzyl chloroformate 
• 328-50-7 α-ketoglutaric acid 
• 621-84-1 O-benzyl carbamate 

Downstream Products

• 108049-92-9 2-oxo-glutaric acid 1-p-nitrobenzyl ester 
• 104754-70-3 erythro, threo-DL-N-benzyloxycarbonyl-α-amino-2-(p-methoxybenzyl)-3-oxo-5-isoxazolidineacetic acid o-nitrobenzyl ester 
• 104754-69-0 N-benzyloxycarbonyl-α-(o-nitrobenzyl)-(Z)-α,β-dehydroglutanic-γ-(N-p-methoxybenzyl)hydroxamic acid 
• 76843-81-7 erythro-DL-N-benzyloxycarbonyl-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid o-nitrobenzyl ester 
• 76843-81-7 threo-DL-N-benzyloxycarbonyl-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid o-nitrobenzyl ester 
• 105933-67-3 N-benzyloxycarbonyl-α-(o-nitrobenzyl)-(Z)-α,β-dehydroglutamate 
• 76843-83-9 erythro-DL-N-benzyloxycarbonyl-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid 
• 76843-83-9 threo-DL-N-benzyloxycarbonyl-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid 
• 104754-59-8 erythro, threo-DL-N-benzyloxycarbonyl-α-amino-2-(p-methoxy-benzyl)-3-oxo-5-isoxazolidine acetic acid benzyl ester 
• 104754-57-6 N-benzyloxycarbonyl-α-benzyl-(Z)-α,β-dehydroglutamic-γ-N-(p-methoxybenzyl)hydroxamic acid 
• 104754-56-5 N-benzyloxycarbonyl-α-benzyl-(Z)-α,β-dehydroglutamic-γ-(N-hydroxysuccinimide)ester 
• 80148-34-1 threo-DL-N-benzyloxycarbonyl-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid diphenylmethyl ester 
• 80132-10-1 threo-DL-N-benzyloxycarbonyl-α-amino-3-oxo-5-isoxazolidineacetic acid diphenylmethyl ester 
• 104754-58-7 erythro, threo-DL-N-benzyloxycarbonyl-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid benzyl ester 

Relevant articles and documents

TOTAL SYNTHESIS OF ANTITUMOR AGENT AT-125, (αS,5S)-α-AMINO-3-CHLORO-4,5-DIHYDRO-5-ISOXAZOLEACETIC ACID

A short and efficient total synthesis of racemic AT-125 and its racemic threo isomer proceeds via an intramolecular Michael cyclization of a protected α,β-dehydroglutamic acid γ-hydroxamate.Separation of diastereomers and deprotection to racemic AT-125 followed by enzymatic resolution of the N-chloroacetamide with hog-kidney acylase provides the natural αS,5S isomer.