Uprosertib, also known as pan-Akt inhibitor, is a pharmaceutical compound that selectively targets and inhibits the activity of serine/threonine protein kinases, specifically the Akt family. Akt kinases are crucial in various cellular processes, including cell survival and apoptosis. Uprosertib's ability to inhibit these kinases makes it a potential candidate for therapeutic applications in various conditions.
1047634-65-0
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Basic information
- Product Name: GSK2141795
- Synonyms: GSK2141795;Uprosertib;Uprosertib(GSK2141795);Uprosertib , GSK2141795C;GSK 2141795C;N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furancarboxamide;Uprosertib, 98%, a potent and selective pan-Akt inhibitor
- CAS NO:1047634-65-0
- Molecular Formula: C18H16Cl2F2N4O2
- Molecular Weight: 429.2480464
- EINECS: N/A
- Product Categories: API
- Mol File: 1047634-65-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: GSK2141795(CAS DataBase Reference)
- NIST Chemistry Reference: GSK2141795(1047634-65-0)
- EPA Substance Registry System: GSK2141795(1047634-65-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1047634-65-0(Hazardous Substances Data)
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1047634-65-0 Usage
Uses
Used in Pharmaceutical Industry:Uprosertib is used as a therapeutic agent for targeting the Akt signaling pathway, which is often dysregulated in various diseases, particularly in cancer. By inhibiting the Akt pathway, Uprosertib can potentially disrupt the cell survival mechanisms and promote apoptosis in cancer cells, making it a promising candidate for cancer treatment.
Additionally, Uprosertib's role in modulating the Akt pathway could also make it useful in other applications where the Akt pathway is implicated, such as in the treatment of neurodegenerative diseases, cardiovascular conditions, and autoimmune disorders. Further research and clinical trials are necessary to explore these potential applications fully.
Check Digit Verification of cas no
The CAS Registry Mumber 1047634-65-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,7,6,3 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.Calculate Digit Verification of CAS Registry Number 1047634-65:
(9*1)+(8*0)+(7*4)+(6*7)+(5*6)+(4*3)+(3*4)+(2*6)+(1*5)=150
150 % 10 = 0
So 1047634-65-0 is a valid CAS Registry Number.
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