1047635-80-2
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Basic information
- Product Name: GSK2141795 (hydrochloride)
- Synonyms: GSK2141795 (hydrochloride);Uprosertib HCl salt , GSK2141795C HCl salt;GSK2141795 HCl
- CAS NO:1047635-80-2
- Molecular Formula: C18H17Cl3F2N4O2
- Molecular Weight: 465.7089864
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1047635-80-2.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: GSK2141795 (hydrochloride)(CAS DataBase Reference)
- NIST Chemistry Reference: GSK2141795 (hydrochloride)(1047635-80-2)
- EPA Substance Registry System: GSK2141795 (hydrochloride)(1047635-80-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1047635-80-2(Hazardous Substances Data)
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General Description
Uprosertib hydrochloride, also known as GSK2141795, is a highly potent and selective inhibitor of the serine/threonine protein kinase AKT. It acts as an ATP-competitive inhibitor and has shown promising results in preclinical studies for the treatment of cancer. Uprosertib hydrochloride has demonstrated the ability to inhibit the growth of various cancer cell lines, both in vitro and in vivo, by blocking the AKT pathway, which plays a crucial role in cell survival and proliferation. Clinical trials are ongoing to assess the efficacy and safety of this compound as a potential treatment for various types of cancer, including breast, ovarian, and prostate cancer.Check Digit Verification of cas no
The CAS Registry Mumber 1047635-80-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,7,6,3 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1047635-80:
(9*1)+(8*0)+(7*4)+(6*7)+(5*6)+(4*3)+(3*5)+(2*8)+(1*0)=152
152 % 10 = 2
So 1047635-80-2 is a valid CAS Registry Number.
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GSK2141795 (hydrochloride)
