1047677-46-2Relevant academic research and scientific papers
NOVEL SUBSTITUTED BIS-1, 2, 4-TRIOXANES AND A PROCESS FOR PREPARATION THEREOF
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, (2008/12/08)
The present invention relates to novel substituted bis-1, 2, 4-trioxanes i.e. compounds containing two 1, 2, 4-trioxane moieties of general formula (6) useful as antimalarial agents. This invention also relates to a process for the preparation of novel su
Novel bis- and tris-1,2,4-trioxanes: Synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in swiss mice
Singh, Chandan,Verma, Ved Prakash,Naikade, Niraj Krishna,Singh, Ajit Shankar,Hassam, Mohammad,Puri, Sunil K.
experimental part, p. 7581 - 7592 (2009/11/30)
A new series of bis-1,2,4-trioxanes 12a-h, 13a-h, and 14a-h and tris-1,2,4-trioxanes 12i-14i were prepared and evaluated against multidrug-resistant Plasmodium yoelii in Swiss mice by oral route. Cyclopentane-based bis-trioxanes 12a, 12b, 12f-h and cycloh
