104776-74-1Relevant articles and documents
Discovery of substituted (2‐aminooxazol‐4‐yl)isoxazole‐3‐ carboxylic acids as inhibitors of bacterial serine acetyltransferase in the quest for novel potential antibacterial adjuvants
Magalh?es, Joana,Franko, Nina,Raboni, Samanta,Annunziato, Giannamaria,Tammela, P?ivi,Bruno, Agostino,Bettati, Stefano,Armao, Stefano,Spadini, Costanza,Cabassi, Clotilde Silvia,Mozzarelli, Andrea,Pieroni, Marco,Campanini, Barbara,Costantino, Gabriele
, p. 1 - 16 (2021/03/16)
Many bacteria and actinomycetales use L‐cysteine biosynthesis to increase their tolerance to antibacterial treatment and establish a long‐lasting infection. In turn, this might lead to the onset of antimicrobial resistance that currently represents one of
Synthesis and pharmacological characterization of new analogs of broxaterol
De Amici,Conti,Dallanoce,Kassi,Castellano,Stefancich,De Micheli
, p. 69 - 80 (2007/10/03)
A series of isoxazole derivatives structurally related to broxaterol 1 has been prepared and tested for their potency to β1 and β2 adrenergic receptors. At variance with broxaterol, none of the tested compounds displayed agonistic activity. The 3-isopropenyl derivative 5f is the most potent antagonist both in the trachea and atria preparations.
Synthesis of New Isoxazole Aminoalcohols
Chiarino, D.,Fantucci, M.,Sala, A.,Veneziani, C.
, p. 337 - 342 (2007/10/02)
The preparation of new 1-isoxazolyl-2-amino-1-ethanol derivatives is described starting from the corresponding 1-isoxazolylethanones.It is also reported the synthesis of 1-(5-isoxazolyloxy)-3-amino-2-propanol compounds starting from the corresponding 5-ha