104777-68-6

Basic information

• Product Name: plantamajoside
• Synonyms: plantamajoside;2-(3,4-Dihydroxyphenyl)ethyl 4-O-(3,4-dihydroxycinnamoyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranoside;Plantamoside;2-(3,4-Dihydroxyphenyl)ethyl 3-O-beta-D-glucopyranosyl-beta-D-glucopyranoside 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate];Purpureaside A;dihoside A;(E)-6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((3,4,5-trihydroxy-6-(hydroxymet;Plantamajoside, 98%, from Plantago major L.
• CAS NO: 104777-68-6
• Molecular Formula: C₂₉H₃₆O₁₆
• Molecular Weight: 640.6
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 104777-68-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 953°Cat760mmHg
• Flash Point: 308.4°C
• Appearance: /
• Density: 1.66
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.705
• Storage Temp.: 2-8°C
• PKA: 9.31±0.10(Predicted)
• CAS DataBase Reference: plantamajoside(CAS DataBase Reference)
• NIST Chemistry Reference: plantamajoside(104777-68-6)
• EPA Substance Registry System: plantamajoside(104777-68-6)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 104777-68-6(Hazardous Substances Data)

Usage

General Description

Plantamajoside is a natural chemical compound found in several plant species, including Plantago major and Scrophularia buergeriana. It is a type of iridoid glycoside, known for its anti-inflammatory, antioxidant, and wound-healing properties. Plantamajoside has been extensively studied for its potential therapeutic applications in the treatment of various inflammatory conditions, including skin disorders, arthritis, and other inflammatory diseases. It has been shown to inhibit the production of inflammatory mediators and reduce oxidative stress in the body. Additionally, plantamajoside has been found to promote the healing of wounds and improve skin health. Overall, the compound shows promise as a natural remedy for inflammation-related ailments and may have potential uses in the development of pharmaceutical and skincare products.

InChI:InChI=1/C29H36O16/c30-11-19-22(37)23(38)24(39)29(42-19)45-27-25(40)28(41-8-7-14-2-5-16(33)18(35)10-14)43-20(12-31)26(27)44-21(36)6-3-13-1-4-15(32)17(34)9-13/h1-6,9-10,19-20,22-35,37-40H,7-8,11-12H2/b6-3+/t19-,20-,22-,23+,24-,25-,26-,27-,28-,29+/m1/s1

Upstream product

• 104777-69-7 3,4-dihydroxy-β-phenethyl-O-β-D-glucopyranosyl-(1->3)-O-α-rhamnopyranosyl-(1->6)-4-caffeoyl-β-D-glucopyranoside 

Downstream Products

• 331-39-5 caffeic acid 

Related news

plantamajoside (cas 104777-68-6) inhibits lipopolysaccharide-induced epithelial-mesenchymal transition through suppressing the NF-κB/IL-6 signaling in esophageal squamous cell carcinoma cells09/06/2019

Plantamajoside (PMS) is a major compound of Plantago asiatica and possesses anti-tumor activity. However, the effect of PMS on esophageal squamous cell carcinoma (ESCC) and the underlying mechanism of action are unclear. The present study aimed to evaluate the effect of PMS on lipopolysaccharide...detailed

Nephroprotection of plantamajoside (cas 104777-68-6) in rats treated with cadmium09/05/2019

Cadmium (Cd), an environmental and industrial pollutant, generates free radicals responsible for oxidative stress. Cd can also lead to various renal toxic damage such as the proximal tubules and glomerulus dysfunction. Plantamajoside (PMS), a major compound of Plantago asiatica (PA), was reporte...detailed

Pharmacokinetics of plantamajoside (cas 104777-68-6) and acteoside from Plantago asiatica in rats by liquid chromatography–mass spectrometry09/04/2019

Plantago asiatica is a medicinal and dietary plant rich in polyphenolic compounds such as phenylpropanoid glycosides plantamajoside and acteoside. The aims of the present study were to develop a new and sensitive method for simultaneous determination of plantamajoside and acteoside and investiga...detailed

plantamajoside (cas 104777-68-6) ameliorates lipopolysaccharide-induced acute lung injury via suppressing NF-κB and MAPK activation09/03/2019

Despite developments in the knowledge and therapy of acute lung injury in recent decades, mortality remains high, and there is usually a lack of effective therapy. Plantamajoside, a major ingredient isolated from Plantago asiatica L. (Plantaginaceae), has been reported to have potent anti-inflam...detailed

plantamajoside (cas 104777-68-6) attenuates isoproterenol-induced cardiac hypertrophy associated with the HDAC2 and AKT/ GSK-3β signaling pathway09/01/2019

As a compensatory response to cardiac overload, cardiac hypertrophy is closely associated with the occurrence and development of a variety of cardiovascular diseases, in which histone deacetylase 2 (HDAC2) has been reported to play an important role. Plantamajoside (PMS) is an active component e...detailed

plantamajoside (cas 104777-68-6) attenuates inflammatory response in LPS-stimulated human gingival fibroblasts by inhibiting PI3K/AKT signaling pathway08/31/2019

Periodontitis is an important inflammatory disease that often causes by periodontopathic bacteria. The present study, we tested the anti-inflammatory effects of plantamajoside on LPS-stimulated human gingival fibroblasts. Human gingival fibroblasts (HGFs) were stimulated with LPS from Porphyromo...detailed

Relevant articles and documents

FOUR CAFFEOYL GLYCOSIDES FROM CALLUS TISSUE OF REHMANNIA GLUTINOSA

From the methanolic extract of callus tissue of Rehmannia glutinosa four phenolic glycosides and one aliphatic glycoside were isolated.Two of the phenolic glycosides were identified as acteoside and forsythiaside and the structures of the other two were elucidated as 3,4-dihydroxy-β-phenethyl-O-β-D-glucopyranosyl-(1->3)-4-O-caffeoyl-β-D-glucopyranosideand 3,4-dihydroxy-O-β-D-glucopyranosyl-(1->3)-α-L-rhamnopyranosyl-(1->6)-4-O-caffeoyl-β-D-glucopyranoside.