104777-77-7 Usage
Uses
Used in Pharmaceutical Industry:
4-Hydroxytranylcypromine is used as a key compound in the preparation of heteroaryl cyclopropylamines. These heteroaryl cyclopropylamines are selective lysine-specific demethylase-1 (LSD1) inhibitors, which play a crucial role in the development and progression of cancer. By inhibiting LSD1, these compounds can potentially suppress tumor growth and improve the effectiveness of cancer treatments.
Additionally, 4-hydroxytranylcypromine and its derivatives have shown promise in the treatment of viral infections. The compound's unique structure allows it to interact with specific viral proteins, disrupting their function and potentially inhibiting the replication of the virus. This makes it a valuable tool in the development of new antiviral therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 104777-77-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,7,7 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 104777-77:
(8*1)+(7*0)+(6*4)+(5*7)+(4*7)+(3*7)+(2*7)+(1*7)=137
137 % 10 = 7
So 104777-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO/c10-9-5-8(9)6-1-3-7(11)4-2-6/h1-4,8-9,11H,5,10H2/t8-,9+/m0/s1
104777-77-7Relevant academic research and scientific papers
LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE
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Page/Page column 89-90, (2011/04/24)
The invention relates to a compound of Formula (I): (A')x-(A)-(B)-(Z)-(L)-(D), wherein: (A) is heteroaryl or aryl; each (A'), if present, is independently chosen from aryl, arylalkoxy, arylalkyl, heterocyclyl, aryloxy, halo, alkoxy, haloalkyl,
LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE
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Page/Page column 88-89, (2011/11/06)
The present invention relates to a compound of Formula 1, wherein: (A) is heteroaryl or aryl; each (Α'), if present, is independently chosen from aryl, arylalkoxy, arylalkyl, heterocyclyl, aryloxy, halo, alkoxy, haloalkyl, cycloalkyl, haloalkoxy, and cyan