1047997-69-2Relevant academic research and scientific papers
Synthesis and bioactivity of N-tert-butyl-N′-acyl-5-methyl-1,2,3- thiadiazole-4-carbohydrazides
Mao, Wu Tao,Zhao, Hui,Fan, Zhi Jin,Ji, Xiao Tian,Hua, Xue Wen,Kalinina, Tatiana,Yury, Yu. Morzherin,Vasiliy, A. Bakulev
, p. 1233 - 1236,4 (2020/10/15)
A series of novel N-tert-butyl-N′-acyl-5-methyl-1,2,3-thiadiazole-4- carbohydrazides were designed and synthesized. Their structures were characterized by melting points, 1H NMR, IR, ESI-MS, and elemental analysis. The bioassay tests indicated that compound 7o exhibited excellent direct anti-TMV activity and induction activity in vivo at 50 μg/mL, which was better than that of Ninamycin and tiadinial. Our studies indicated that 1,2,3-thiadiazole was an active substructure for novel pesticide development.
Synthesis and insecticidal activity of N - Tert -Butyl- N, N ′-diacylhydrazines containing 1,2,3-thiadiazoles
Wang, Huan,Yang, Zhikun,Fan, Zhijin,Wu, Qingjun,Zhang, Youjun,Mi, Na,Wang, Shouxin,Zhang, Zhengcai,Song, Haibin,Liu, Feng
experimental part, p. 628 - 634 (2011/10/02)
N-tert-Butyl-N,N′-diacylhydrazines are nonsteroidal ecdysone agonists used as environmental benign pest regulators. In this paper, two series of new N-tert-butyl-N,N′-diacylhydrazine derivatives containing 1,2,3-thiadiazole were designed and synthesized.
Synthesis, crystal structure and biological activity of N′-tert-butyl-N-(3-methoxylbenzoyl)-N-(4-methyl-1,2, 3-thiadiazole-5- formylhydrazine
Huang, Jie,Wang, Huan,Fan, Zhi-Jin,Song, Hai-Bin,Zhao, Hui,Huang, Yun,Prokhorova, Polina E.,Belskaya, Nataliya P.,Morzherin, Yury Yu.,Bakulev, Vasiliy A.
experimental part, p. 1860 - 1865 (2012/03/26)
The title compound, N'-tert-butyl-N-(3-methoxylbenzoyl)- N-(4-methyl-1,2,3-thiadiazole-5-formylhydrazine (C16H 20N4O3S) was prepared from the reaction of 4-methyl-1, 2,3-thiadiazole-5-carbonyl chloride with N'-tert-Butyl-3- methoxylbenzohydrazine, and its structure was characterized by 1Hydrogen Nuclear Magnetic Resonance, High-Resolution Mass Spectrometry, IR spectra, and single crystal X-ray diffraction. The crystal of the title compound belongs to monoclinic system, space group P 21/c with cell parameters a = 17.986(2) A, b = 8.0180(10) A, c = 12.0190(14) A, α = 90°, β = 91.160(5)°, γ = 90°, V = 1732.9(4) A 3, Z = 4, Dc = 1.335 g/cm3, l (Mo Ka) = 0.209 mm-1, F (000) = 736, R = 0.0367 and wR = 0.0932. X-ray diffraction analysis indicates that all rings in the title compound are non-planar. The bioassay results indicated that, the title compound had good fungicide activity against Sclerotinia sclerotiorum, certain extent of insecticidal activity against Plutella xylostella L. Springer Science+Business Media, LLC 2011.
