Welcome to LookChem.com Sign In|Join Free
  • or
AB 1010 Mesylate is a novel tyrosine kinase inhibitor that targets Kit and PDGFRα/β with IC50 values of 200 nM and 540 nM/800 nM, respectively. It is a promising pharmaceutical candidate with potential applications in various industries.
Used in Pharmaceutical Industry:
AB 1010 Mesylate is used as a tyrosine kinase inhibitor for the treatment of various diseases, including sickle cell disease. It works by inhibiting the activity of Kit and PDGFRα/β, which are involved in the pathogenesis of these conditions.
Used in Cancer Treatment:
AB 1010 Mesylate is used as a potential anticancer agent, as it can inhibit the activity of tyrosine kinases that are often dysregulated in cancer cells. This can lead to the suppression of tumor growth and progression.
Used in Drug Delivery Systems:
To enhance the efficacy and bioavailability of AB 1010 Mesylate, various drug delivery systems can be employed. These systems can include organic and metallic nanoparticles, which can improve the delivery of AB 1010 Mesylate to target cells and tissues, leading to better therapeutic outcomes.

1048007-93-7

Post Buying Request

1048007-93-7 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

1048007-93-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1048007-93-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,0,0 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1048007-93:
(9*1)+(8*0)+(7*4)+(6*8)+(5*0)+(4*0)+(3*7)+(2*9)+(1*3)=127
127 % 10 = 7
So 1048007-93-7 is a valid CAS Registry Number.

1048007-93-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methanesulfonic acid,4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide

1.2 Other means of identification

Product number -
Other names 4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)benzamide mesylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1048007-93-7 SDS

1048007-93-7Downstream Products

1048007-93-7Relevant academic research and scientific papers

PROCESS FOR THE SYNTHESIS OF 2-AMINOTHIAZOLE COMPOUNDS AS KINASE INHIBITORS

-

Page/Page column 23, (2008/12/08)

The present invention relates to an industrial process of preparing pharmaceutical compounds having the formula (I) which are useful as certain tyrosine kinase inhibitors and more particularly as c-kit and bcr-abl inhibitors. The groups R1 and R2, identical or different, represent each a hydrogen, halogen atom, an alkyl, an alkoxy, a trifluoromethyl, an amino, an alkylamino, a dialkylamino, a solubilising group; m is 0-5 and n is 0-4; the group R3 represents an aryl or an heteroaryl group as described in claims herein.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 1048007-93-7