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tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1048039-49-1 Structure
  • Basic information

    1. Product Name: tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate
    2. Synonyms: tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate
    3. CAS NO:1048039-49-1
    4. Molecular Formula:
    5. Molecular Weight: 377.609
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1048039-49-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate(1048039-49-1)
    11. EPA Substance Registry System: tert-butyl 5-chloro-3-iodo-1H-indole-1-carboxylate(1048039-49-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1048039-49-1(Hazardous Substances Data)

1048039-49-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1048039-49-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,0,3 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1048039-49:
(9*1)+(8*0)+(7*4)+(6*8)+(5*0)+(4*3)+(3*9)+(2*4)+(1*9)=141
141 % 10 = 1
So 1048039-49-1 is a valid CAS Registry Number.

1048039-49-1Relevant articles and documents

Lynamicin D an antimicrobial natural product affects splicing by inducing the expression of SR protein kinase 1

Sigala, Ioanna,Ganidis, George,Thysiadis, Savvas,Zografos, Alexandros L.,Giannakouros, Thomas,Sarli, Vasiliki,Nikolakaki, Eleni

, p. 1622 - 1629 (2017)

The first total synthesis of the antimicrobial natural product lynamicin D has been developed using a Suzuki coupling to construct the bisindole pyrrole skeleton. An evaluation of the biological activity of lynamicin D reveals that it has a minor effect on cell viability but it can modulate splicing of pre-mRNAs. We provide evidence that this effect is mainly due to the ability of lynamicin D to alter the levels of SRPK1, the key kinase involved in both constitutive and alternative splicing.

SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF

-

, (2020/12/10)

Disclosed are a class of SMAC mimetics used as IAP inhibitors, and in particular disclosed are compounds as shown in formula (I), isomers thereof, and pharmaceutically acceptable salts thereof. The IAP inhibitors are drugs for treating cancers, in particu

COMPOUNDS AND METHOD OF USE

-

, (2019/09/06)

This present disclosure relates to compounds with ferroptosis inducing activity, a method of treating a subject with cancer with the compounds, and combination treatments with a second therapeutic agent.

One-pot synthesis of camalexins and 3,3′-biindoles by the Masuda borylation-Suzuki arylation (MBSA) sequence

Tasch, Boris O. A.,Antovic, Dragutin,Merkul, Eugen,Mueller, Thomas J. J.

, p. 4564 - 4569 (2013/07/26)

The Masuda borylation/Suzuki arylation (MBSA) sequence starting from N-protected 3-iodoindoles has successfully been extended to the coupling of five-membered heterocycles and indoles in the arylation step, which could not be achieved with previously developed MBSA methods. By this approach the one-pot nature of the method as well as the use of a simple catalyst system has been retained. The applicability of the method has been demonstrated by the facile synthesis of camalexins and 3,3′-biindoles, compounds of special interest due to their pronounced antifungal, antimicrobial and cytotoxic activities. The Masuda borylation/Suzuki arylation sequence furnishes in a concise one-pot manner camalexins and 3,3′-biindoles, compounds that show pronounced antifungal, antimicrobial, and cytotoxic activities. Copyright

One-pot synthesis of diazine-bridged bisindoles and concise synthesis of the marine alkaloid hyrtinadine A

Tasch, Boris O. A.,Merkul, Eugen,Mueller, Thomas J. J.

, p. 4532 - 4535 (2011/10/03)

Diazine-bridged bisindoles are readily obtained from N-Bocprotected 3-iodoindoles and 3-iodo-7-azaindole in a pseudo three-component reaction involving a one-pot Masuda borylation-Suzuki arylation sequence. Some of the title com-pounds display promising c

Amino-zinc-ene-enolate cyclization: A short access to cis-3-substituted prolino-homotryptophane derivatives

Mothes, Celine,Lavielle, Solange,Karoyan, Philippe

, p. 6706 - 6710 (2008/12/22)

(Chemical Equation Presented) Proline chimeras are useful tools for medicinal chemistry and/or biological applications. The asymmetric synthesis of cis-3-substituted prolines can be easily achieved via amino-zinc-ene-enolate cyclization followed by transm

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