104807-65-0 Usage
General Description
Ethyl 2-iodo-5-methoxybenzoate is a chemical compound with the molecular formula C10H11IO3. It is derived from benzoic acid and is a member of the ester class of compounds. The presence of an ethyl group, an iodine atom, and a methoxy group gives this compound its unique properties. Ethyl 2-iodo-5-methoxybenzoate is frequently used in organic synthesis and pharmaceutical research due to its potential as a building block for more complex molecules. It has also been studied for its potential biological and pharmacological activities, although its precise uses in these fields are still being researched.
Check Digit Verification of cas no
The CAS Registry Mumber 104807-65-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,8,0 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 104807-65:
(8*1)+(7*0)+(6*4)+(5*8)+(4*0)+(3*7)+(2*6)+(1*5)=110
110 % 10 = 0
So 104807-65-0 is a valid CAS Registry Number.
104807-65-0Relevant articles and documents
One-Pot C-H Arylation/Lactamization Cascade Reaction of Free Benzylamines
Chand-Thakuri, Pratibha,Landge, Vinod G.,Kapoor, Mohit,Young, Michael C.
, p. 6626 - 6644 (2020/07/14)
An efficient method has been developed for the synthesis of seven-membered biaryl lactams involving Pd-catalyzed, native amine-directed, ortho-arylation of benzylamines followed by in situ lactamization. This cascade sequence is enabled by the use of 2-iodobenzoates, which facilitates C-H arylation from the free amine under conditions that typically require an improved directing group approach. This reaction is characterized by a broad substrate scope with good functional group tolerance. The need for an ester versus carboxylic acid-functionalized coupling partner is also explored, as is the potential for synthesizing eight-membered biaryl lactams. Various applications are also investigated, including access to the aza-brassinolide core.
