104809-18-9

Basic information

• Product Name: 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT
• Synonyms: 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT;7-methylguanosine 5'-triphosphate*sodium approx.;7-METHYLGUANOSINE 5'-TRIPHOSPHATE*SODIUM APPROX. 90;m7GTP;7-Methylguanosine 5′-triphosphate
• CAS NO: 104809-18-9
• Molecular Formula: C11H18N4NaO14P3
• Molecular Weight: 546.19
• Product Categories: Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Nucleotide Analogs
• Mol File: 104809-18-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT(104809-18-9)
• EPA Substance Registry System: 7-METHYLGUANOSINE 5'-TRIPHOSPHATE SODIUM SALT(104809-18-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 104809-18-9(Hazardous Substances Data)

Usage

Uses

7-Methylguanosine 5′-triphosphate (m7GTP) is use to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP may be used to create affinity media for capture and purification of molecules such as eukaryotic initiation factor eIF4E.

General Description

7-Methylguanosine 5′-triphosphate is a mRNA cap structural analog.

Biochem/physiol Actions

7-Methylguanosine 5′-triphosphate (m7GTP) inhibits in vitro protein synthesis by binding to translation initiation complexes. m7GTP is useful to study the structures and mechanisms of eukaryotic cellular mRNA caps in the context of mRNA involvement in protein synthesis. m7GTP has a high affinity for eukaryotic initiation factor eIF4E and may be used to create affinity media for their capture and purification.