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1048107-99-8

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1048107-99-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1048107-99-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,1,0 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1048107-99:
(9*1)+(8*0)+(7*4)+(6*8)+(5*1)+(4*0)+(3*7)+(2*9)+(1*9)=138
138 % 10 = 8
So 1048107-99-8 is a valid CAS Registry Number.

1048107-99-8Relevant articles and documents

DIAMINOPROPANE DERIVED MACROCYCLES AS INHIBITORS OF BETA AMYLOID PRODUCTION

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Page/Page column 30-31, (2008/12/07)

There is provided a series of macrocyclic diaminopropanes of Formula (I) or a stereoisomer; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, m, n, W, X, Y, Z and L as defined herein, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor protein (APP) by β-secretase and, more specifically, inhibit the production of Aβ-peptide. The present disclosure is directed to compounds useful in the treatment of neurological disorders related to β-amyloid production, such as Alzheimer's disease and other conditions affected by anti-amyloid activity.

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