104820-14-6Relevant articles and documents
Indeno[1,2-b]pyrazin-2,3-diones: A new class of antagonists at the glycine site of the NMDA receptor with potent in vivo activity
Jimonet, Patrick,Ribeill, Yves,Bohme, Georg Andrees,Boireau, Alain,Chevé, Michel,Damour, Dominique,Doble, Adam,Genevois-Borella, Arielle,Herman, Frédéric,Imperato, Assunta,Le Guern, Sylvain,Manfré, Franco,Pratt, Jeremy,Randle, John C. R.,Stutzmann, Jean-Marie,Mignani, Serge
, p. 2371 - 2381 (2000)
Indeno[1,2-b]pyrazin-2,3-diones have been identified as a novel series of potent ligands on the glycine site of the NMDA receptor. To improve their in vivo activities, an acetic acid-type side chain was introduced to the 5- position, giving water-soluble