104830-16-2Relevant articles and documents
A convenient approach to δ-amino-β-ketoesters by vinylogous Mannich reaction of masked acetoacetates
Villano, Rosaria,Acocella, Maria Rosaria,Massa, Antonio,Palombi, Laura,Scettri, Arrigo
, p. 12317 - 12323 (2007)
SiCl4 is an efficient and selective catalyst for the vinylogous Mannich reaction of linear and cyclic synthetic equivalents of acetoacetate dianion, leading to δ-amino-β-ketoesters in moderate to high yields and complete γ-selectivity; anti-diastereoselectivity was observed by using a γ-methyl-substituted cyclic silyloxydiene.