104832-93-1

Upstream product

• 2033-89-8 3,4-dimethoxyphenol 
• 6380-24-1 (Z)-1,2-dimethoxy-4-(prop-1-en-1-yl)benzene 
• 6379-72-2 1,2-dimethoxy-4-(E)-propenylbenzene 
• 104761-76-4 3,4,5-trimethoxycinnamyl 3,4-dimethoxyphenyl ether 
• 1504-56-9 (E)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ol 
• 20329-98-0 (E)-3,4,5-trimethoxy-cinnamic acid 

Relevant academic research and scientific papers

Mechanistic Aspects and Synthetic Applications of the Electrochemical and Iodobenzene Bis(trifluoroacetate) Oxidative 1,3-Cycloadditions of Phenols and Electron-Rich Styrene Derivatives

Anodic oxidation of p-methoxy-substituted phenols and electron-rich styrene or propenylbenzene derivatives affords in good yield trans-dihydrobenzofurans derived from a formal 1,3-oxidative cycloaddition of the phenol to the styrene derivative.The yield o

A Convergent Route to Dihydrobenzofuran Neolignans via a Formal 1,3-Cycloaddition to Oxidized Phenols

Oxidation of p-methoxy-substituted phenols with iodobenzene bis-trifluoroacetate in the presence of electron-rich styrene derivatives affords trans-dihydrobenzofurans stereoselectively.

Structure-Activity Relationships of Kadsurenone Analogues

Kadsurenone, a specific receptor antagonist of platelet-activating factor (PAF), and its analogues were prepared from derivatives of cinnamyl alcohol and (allyloxy)phenol.Racemic kadsurenone, resolvable by a Chiralpak column at low temperatures, has an IC50 value of 2 * 10-7 M, which is about 50percent of the activity of the natural product (IC50 = 1 * 10-7 M).The structural specificity of kadsurenone was further demonstrated by the low PAF-receptor-blocking activities of denudatin B, mirandin A, desallylkadsurenone, and the 2-epimer of kadsurenone.