1048329-83-4Relevant academic research and scientific papers
Regioselective synthesis of γ-amino esters, nitriles, sulfones, and pyrrolidinones by nickel-catalyzed reductive coupling of aldimines and activated alkenes
Yeh, Chien-Hung,Korivi, Rajendra Prasad,Cheng, Chien-Hong
supporting information; experimental part, p. 4892 - 4895 (2009/02/08)
(Chemical Equation Presented) A couple of alternatives: An efficient method has been developed for the synthesis of γ-amino derivatives and pyrrolidinones from readily available starting materials by using a nickel-phenanthroline complex (see scheme). The reaction proceeds by the formation of a C-C bond at the β-carbon atom, instead of the more usual α-carbon atom, of a conjugated alkene via an azanickelacycle intermediate.
