1048334-80-0

Basic information

• Product Name: (R)-3-{11-[4-(2-bromophenoxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-1-oxo-1,2,3,4,5,11-hexahydrodibenzo[b,e][1,4]diazepin-10-yl}-3-oxopropionic acid
• CAS NO: 1048334-80-0
• Molecular Weight: 625.903
• Mol File: 1048334-80-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-{11-[4-(2-bromophenoxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-1-oxo-1,2,3,4,5,11-hexahydrodibenzo[b,e][1,4]diazepin-10-yl}-3-oxopropionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-{11-[4-(2-bromophenoxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-1-oxo-1,2,3,4,5,11-hexahydrodibenzo[b,e][1,4]diazepin-10-yl}-3-oxopropionic acid(1048334-80-0)
• EPA Substance Registry System: (R)-3-{11-[4-(2-bromophenoxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-1-oxo-1,2,3,4,5,11-hexahydrodibenzo[b,e][1,4]diazepin-10-yl}-3-oxopropionic acid(1048334-80-0)

Safety Data

• Hazardous Substances Data: 1048334-80-0(Hazardous Substances Data)

Upstream product

• 1048334-65-1 3-{11-[4-(2-bromophenoxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-1-oxo-1,2,3,4,5,11-hexahydrodibenzo[b,e][1,4]diazepin-10-yl}-3-oxopropionic acid 
• 1048334-57-1 11-[4-(2-bromophenoxy)-2-chlorophenyl]-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one 
• 1048334-64-0 10-(3-oxo-3-methoxypropionyl)-11-[4-(2-bromophenoxy)-2-chloro-phenyl]-6-hydroxy-3,3-dimethyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]diazepin-1-one 

Relevant articles and documents

6-HYDROXY-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS

Inhibitors of HCV replication of formula (I) the stereoisomers, prodrugs, tautomers, racemics, salts, hydrates or solvates thereof wherein R1, R2; R3; R4a and R4b have the meaning defined in the claims.The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.