1048366-77-3Relevant academic research and scientific papers
Discovery of benzothiazole derivatives as efficacious and enterocyte-specific MTP inhibitors
Vu, Chi B.,Milne, Jill C.,Carney, David P.,Song, Jeffrey,Choy, Wendy,Lambert, Philip D.,Gagne, David J.,Hirsch, Michael,Cote, Angela,Davis, Meghan,Lainez, Elden,Meade, Nekeya,Normington, Karl,Jirousek, Michael R.,Perni, Robert B.
scheme or table, p. 1416 - 1420 (2009/11/30)
A series of triamide derivatives bearing a benzothiazole core is shown to be potent microsomal triglyceride transfer protein (MTP) inhibitors. In order to minimize liver toxicity, these compounds have been optimized to have activity only in the enterocyte
GUT MICROSOMAL TRIGLYCERIDE TRANSPORT PROTEIN INHIBITORS
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Page/Page column 118-119, (2008/12/08)
Compounds represented by formula (I): are inhibitors of gut microsomal triglyceride transfer protein. Such compounds are useful in treating diseases or conditions such as diabetes and obesity, along with patients are risk for developing such diseases or conditions.
