1048486-16-3 Usage
Uses
Used in Pharmaceutical Development:
5-(3,4-difluorophenyl)pyridine-3-carboxylic acid is used as a building block or intermediate in the synthesis of pharmaceuticals for various therapeutic applications. Its heterocyclic structure and functional groups may contribute to the development of new drugs with specific biological activities.
Used in Agrochemicals:
In the agrochemical industry, 5-(3,4-difluorophenyl)pyridine-3-carboxylic acid is used as a key component in the creation of pesticides or herbicides. Its chemical properties may provide selective control over pests or unwanted plant growth, contributing to more effective and targeted agricultural solutions.
Used in Academic Research:
5-(3,4-difluorophenyl)pyridine-3-carboxylic acid serves as a valuable compound in academic research, particularly in the fields of organic chemistry, medicinal chemistry, and materials science. Researchers may explore its reactivity, stability, and potential interactions with biological systems to uncover new insights and applications.
Used in Industrial Product Development:
5-(3,4-difluorophenyl)pyridine-3-carboxylic acid may also find use in the development of various industrial products, such as specialty chemicals, coatings, or materials with unique properties. Its aromatic and heterocyclic nature could contribute to the creation of innovative products with improved performance characteristics.
The specific properties and potential uses of 5-(3,4-difluorophenyl)pyridine-3-carboxylic acid would need to be determined through further experimentation and analysis to fully understand its capabilities and limitations in these applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1048486-16-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,4,8 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1048486-16:
(9*1)+(8*0)+(7*4)+(6*8)+(5*4)+(4*8)+(3*6)+(2*1)+(1*6)=163
163 % 10 = 3
So 1048486-16-3 is a valid CAS Registry Number.
1048486-16-3Relevant academic research and scientific papers
Structure-Activity Relationship for the Picolinamide Antibacterials that Selectively Target Clostridioides difficile
Speri, Enrico,Qian, Yuanyuan,Janardhanan, Jeshina,Masitas, Cesar,Lastochkin, Elena,De Benedetti, Stefania,Wang, Man,Schroeder, Valerie A.,Wolter, William R.,Oliver, Allen G.,Fisher, Jed F.,Mobashery, Shahriar,Chang, Mayland
, p. 991 - 995 (2021/05/27)
Clostridioides difficile is a leading health threat. This pathogen initiates intestinal infections during gut microbiota dysbiosis caused by oral administration of antibiotics. C. difficile is difficult to eradicate due to its ability to form spores, which are not susceptible to antibiotics. To address the urgent need for treating recurrent C. difficile infection, antibiotics that selectively target C. difficile over common gut microbiota are needed. We herein describe the class of picolinamide antibacterials which show potent and selective activity against C. difficile. The structure-activity relationship of 108 analogues of isonicotinamide 4, a compound that is equally active against methicillin-resistant Staphylococcus aureus and C. difficile, was investigated. Introduction of the picolinamide core as exemplified by analogue 87 resulted in exquisite potency and selectivity against C. difficile. The ability of the picolinamide class to selectively target C. difficile and to prevent gut dysbiosis holds promise for the treatment of recurrent C. difficile infection.