1048636-96-9Relevant academic research and scientific papers
Triazole-linked analogue of deoxyribonucleic acid (TLDNA): Design, synthesis, and double-strand formation with natural DNA
Isobe, Hiroyuki,Fujino, Tomoko,Yamazaki, Naomi,Guillot-Nieckowski, Marine,Nakamura, Eiichi
supporting information; experimental part, p. 3729 - 3732 (2009/07/01)
(Chemical Equation Presented) A new triazole-linked analogue of DNA ( TLDNA) has been designed and synthesized using click chemistry. The chain elongation reaction using copper-catalyzed Huisgen cycloaddition was successful and gave the artificial oligonucleotide that formed a stable double strand with the complementary strand of natural DNA.
