1048699-20-2Relevant academic research and scientific papers
Design and synthesis of substituted pyrido[3,2-d]-1,2,3-triazines as potential Pim-1 inhibitors
Fan, Yin-Bo,Li, Kun,Huang, Min,Cao, Yu,Li, Ying,Jin, Shu-Yu,Liu, Wen-Bing,Wen, Jia-Chen,Liu, Dan,Zhao, Lin-Xiang
, p. 1224 - 1228 (2016)
A novel series of substituted pyrido[3,2-d]-1,2,3-triazines were designed and synthesized as Pim-1 inhibitors through scaffold hopping. Most of the derivatives showed potent in vitro Pim-1 inhibitory activities and anti-proliferative effects toward prosta
Synthesis and biological evaluation of substituted 1,2,3-benzotriazines and pyrido[3,2-d]-1,2,3-triazines as inhibitors of vascular endothelial growth factor receptor-2
Zhao, Xing-Wang,Liu, Dan,Luan, Sheng-Lin,Hu, Guo-Dong,Lv, Jin-Ling,Jing, Yong-Kui,Zhao, Lin-Xiang
, p. 7807 - 7815 (2014/01/06)
A novel series of substituted 1,2,3-benzotriazines and pyrido[3,2-d]-1,2,3- triazines were synthesized. The abilities of these compounds to inhibit the VEGFR-2 kinase activity and the proliferation of human microvascular endothelial cells (MVECs) were det
AROMATIC RING FUSED TRIAZINE DERIVATIVES AND USES THEREOF
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Page/Page column 14, (2011/08/06)
The invention belongs to pharmaceutical field. The invention relates to the compounds according to Formula I, including their optically active forms, pharmaceutically acceptable salts or hydrates, and the pharmaceutical composition comprising thereof as a
THE AROMATIC RING TRIAZINE DERIVATIVES AND THE USES THEREOF
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Page/Page column 19, (2010/12/01)
The invention belongs to pharmaceutical field. The invention relates to the compounds according to Formula I. including their optically active forms, pharmaceutically acceptable salts or hydrates, and the pharmaceutical composition comprising thereof as a
