104870-02-2

Upstream product

• 133373-56-5 6-(2-Ethyl-phenylamino)-3-methyl-1H-pyrimidine-2,4-dione 
• 586-96-9 Nitrosobenzene 
• 578-54-1 ortho-ethylaniline 
• 116138-07-9 N-(2-Ethyl-phenyl)-benzene-1,2-diamine 
• 116138-06-8 (2-Ethyl-phenyl)-(2-nitro-phenyl)-amine 
• 116138-09-1 10-(2-Ethyl-phenyl)-10H-benzo[g]pteridine-2,4-dione 
• 74-88-4 methyl iodide 
• 4318-56-3 3-methyl-6-chlorouracil 
• 1493-27-2 ortho-nitrofluorobenzene 

Relevant academic research and scientific papers

Flavins as potential antimalarials. 2. 3-Methyl-10-(substituted-phenyl)flavins

A series of 3-methyl-10-(substituted-phenyl)flavins was prepared and tested for antimalarial activity against the lethal parasite Plasmodium vinckei in mice. Several of these analogues were found to be effective antimalarial agents. A quantitative structure-activity relationship study was undertaken with 44 analogues and no satisfactory relationship could be established.

COENZYME MODELS. PART 45. SYNTHESIS OF ATROPISOMERIC FLAVINS AND THEIR NOVEL REDOX-INDUCED RACEMISATION

Seven (5-carba)isoalloxazines with restricted rotation about the C(1')-N(10) single bond were synthesized for the first time.They were optically resolved by a liquid chromatographic method.Six of these atropisomers (92.1-100 percent enantiomeric excess) (