104883-49-0

Basic information

• Product Name: 3-AMINO-OCTANOIC ACID
• Synonyms: 3-AMINO-OCTANOIC ACID;RARECHEM AK ML 0071
• CAS NO: 104883-49-0
• Molecular Formula: C8H17NO2
• Molecular Weight: 159.23
• Mol File: 104883-49-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 273.2 °C at 760 mmHg
• Flash Point: 119 °C
• Appearance: /
• Density: 0.999 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-AMINO-OCTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-OCTANOIC ACID(104883-49-0)
• EPA Substance Registry System: 3-AMINO-OCTANOIC ACID(104883-49-0)

Safety Data

• Hazardous Substances Data: 104883-49-0(Hazardous Substances Data)

Usage

General Description

3-Amino-octanoic acid, also known as omega-aminocaprylic acid, is a chemical compound with the molecular formula C8H17NO2. It is an amino acid derivative that contains a carboxylic acid and an amino group. 3-Amino-octanoic acid is commonly used in the synthesis of pharmaceuticals and as a building block for various organic compounds. It is also found as a natural component in some organisms. 3-Amino-octanoic acid has been studied for its potential therapeutic applications in the treatment of hypertension and other cardiovascular diseases due to its ability to modulate the renin-angiotensin-aldosterone system. Additionally, it has been investigated for its antibacterial and antifungal properties.

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Relevant articles and documents

Total structure and inhibition of tumor cell proliferation of laxaphycins

From a mixed assemblage of Lyngbya majuscula rich marine cyanobacteria, we isolated a series of cell growth inhibitory cyclic peptides, The structures of the two major components, laxaphycins A (1) and B (2), and of two minor peptides, laxaphycins B2 (3) and B3 (4), were determined by spectroscopic methods and degradative analysis. Absolute configurations of natural and nonproteinogenic amino acids were determined by a combination of hydrolysis, synthesis of noncommercial residues, chemical derivatization, and HPLC analysis. The organism producing the laxaphycins was identified as the cyanobacterium Anabaena torulosa. The antiproliferative activity of laxaphycins was investigated on a panel of solid and lymphoblastic cancer cells. Our results demonstrate that in contrast to laxaphycin A, laxaphycin B inhibits the proliferation of sensitive and resistant human cancer cell lines and that this activity is strongly increased in the presence of laxaphycin A. This effect appears to be due to an unusual biological synergism.