1048964-30-2Relevant academic research and scientific papers
Novel H3 receptor antagonists with improved pharmacokinetic profiles
Santora, Vincent J.,Covel, Jonathan A.,Hayashi, Rena,Hofilena, Brian J.,Ibarra, Jason B.,Pulley, Michelle D.,Weinhouse, Michael I.,Semple, Graeme,Ren, Albert,Pereira, Guilherme,Edwards, Jeffrey E.,Suarez, Marissa,Frazer, John,Thomsen, William,Hauser, Erin,Lorea, Jodie,Grottick, Andrew J.
scheme or table, p. 4133 - 4136 (2009/05/30)
A new series of H3 antagonists derived from the natural product Conessine are presented. Several compounds from these new series retain the potency and selectivity of earlier diamine based analogs while exhibiting improved PK characteristics. O
