1048997-29-0Relevant academic research and scientific papers
Exploring 9-benzyl purines as inhibitors of glutamate racemase (MurI) in Gram-positive bacteria
Geng, Bolin,Breault, Gloria,Comita-Prevoir, Janelle,Petrichko, Randy,Eyermann, Charles,Lundqvist, Tomas,Doig, Peter,Gorseth, Elise,Noonan, Brian
, p. 4368 - 4372 (2008)
An early SAR study of a screening hit series has generated a series of 9-benzyl purines as inhibitors of bacterial glutamate racemase (MurI) with micromolar enzyme potency and improved physical properties. X-ray co-crystal EI structures were obtained.
