1049009-49-5

Basic information

• Product Name: 2-Benzoyl-5-broMobenzaldehyde
• Synonyms: 2-Benzoyl-5-broMobenzaldehyde
• CAS NO: 1049009-49-5
• Molecular Formula: C14H9BrO2
• Molecular Weight: 289.128
• Mol File: 1049009-49-5.mol

Chemical Properties

• CAS DataBase Reference: 2-Benzoyl-5-broMobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzoyl-5-broMobenzaldehyde(1049009-49-5)
• EPA Substance Registry System: 2-Benzoyl-5-broMobenzaldehyde(1049009-49-5)

Safety Data

• Hazardous Substances Data: 1049009-49-5(Hazardous Substances Data)

Upstream product

• 1761-61-1 5-bromosalicyclaldehyde 
• 613-94-5 benzoic acid hydrazide 
• 41377-36-0 benzoic acid (5-bromo-2-hydroxy-benzylidene)-hydrazide 

Downstream Products

• 1599446-29-3 5-bromo-1-phenyl-1,3-dihydroisobenzofuran 

Relevant articles and documents

BF3-Etherate-catalyzed tandem reaction of 2-formylarylketones with electron-rich arenes/heteroarenes: An assembly of isobenzofurans

An efficient and BF3·Et2O-catalyzed chemoselective synthesis of diversified 1,3-diarylisobenzofuran in a high yield has been described. The reaction proceeds through sequential hydroarylation-cyclization between 2-formylarylketones and electron-rich arenes/heteroarenes. Advantageous features of the developed methodology include operational simplicity, a broad substrate scope, and applicability towards gram scale synthesis. The utility of isobenzofuran derivatives as the diene was extended to the synthesis of [4+2] cyclo-adducts with DMAD and the synthesis of 1,2-dicarbonylarenes in good yields.

Efficient synthesis of functionalized 1,3-dihydroisobenzofurans from salicylaldehydes: Application to the synthesis of escitalopram

An efficient synthesis of substituted 1,3-dihydroisobenzofurans is developed. In this novel route, o-aroylbenzaldehydes, as key intermediates, can be obtained by lead tetraacetate oxidation of N-aroylhydrazones of salicylaldehydes. The mild and general st

A versatile and regiospecific synthesis of functionalized 1,3-diarylisobenzofurans

(Chemical Equation Presented) A convenient, versatile, and regiospecific synthesis of functionalized 1,3-diarylisobenzofurans has been developed. It involves chemoselective addition of arylmagnesium reagents to the aldehyde function of o-aroylbenzaldehydes, themselves readily obtained by lead tetraacetate oxidation of N-aroylhydrazones of salicylaldehydes. Various functional groups, including nitro, iodo, or ester functionalities, have thus been positioned with complete regiospecificity on the 1,3-diphenylisobenzofuran backbone.