1049009-59-7Relevant academic research and scientific papers
Regiospecific synthesis of functionalised 1,3-diarylisobenzofurans via palladium- and rhodium-catalysed reaction of boronic acids with o-acylbenzaldehydes under thermal or microwave activation
Jacq, Jerome,Bessieres, Bernard,Einhorn, Cathy,Einhorn, Jacques
experimental part, p. 4927 - 4933 (2010/11/19)
Variously substituted 1,3-diarylisobenzofurans have been regiospecifically prepared via palladium- and rhodium-catalysed reaction of functionalised boronic acids onto o-acylbenzaldehydes. Rhodium catalysis has furthermore been improved using microwave act
A versatile and regiospecific synthesis of functionalized 1,3-diarylisobenzofurans
Jacq, Jerome,Einhorn, Cathy,Einhorn, Jacques
supporting information; experimental part, p. 3757 - 3760 (2009/07/01)
(Chemical Equation Presented) A convenient, versatile, and regiospecific synthesis of functionalized 1,3-diarylisobenzofurans has been developed. It involves chemoselective addition of arylmagnesium reagents to the aldehyde function of o-aroylbenzaldehydes, themselves readily obtained by lead tetraacetate oxidation of N-aroylhydrazones of salicylaldehydes. Various functional groups, including nitro, iodo, or ester functionalities, have thus been positioned with complete regiospecificity on the 1,3-diphenylisobenzofuran backbone.
